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Wednesday, September 26, 2012

Mouse holds secret to regrowing skin

A mouse that escapes predators by shedding patches of its skin may shed light on regeneration and could lead to research that one day helps people heal from wounds and disease, scientists say.

Humans and other mammals are generally very limited when it comes to regeneration, but one mammal, the African spiny mouse, can heal wounds much faster than lab mice can, which drew the attention of Ashley Seifert, a regeneration biologist at the University of Florida at Gainesville.

"Mammals have no problem regenerating blood cells or epidermis, or regrowing hair that is plucked out," Seifert said, "but following injury, like the severing of a finger, mammals generally just seal off the wound site and produce scar tissue.

"Compare that to salamanders, who can regenerate entire pieces of tissue on the sides of their bodies, not to mention arms, legs and their brain," Seifert told LiveScience.

Furthermore, in mammals, "in general, the ability to regenerate also declines with age," Seifert said. "Newborn humans can actually regenerate a very small piece of the fingertip, but this ability is lost during childhood development."

Given the general limits of mammals when it comes to regeneration, Seifert was fascinated by tales of the African spiny mouse. While vigorous movement could peel off up to 60 percent of the skin off the backs of these rodents, they could quickly heal these wounds and regrow spiny hairs that covered the lost skin. [ 10 Amazing Animal Abilities ]

Seifert clarified these rodents do not regrow all their lost skin. "They use contraction to constrict the wound site so they don't actually have to regenerate much tissue at all," he explained. "It is the central portion of this wound, the remaining 5 percent, that they regenerate."

To learn more about how these rodents accomplish such regeneration, Seifert and his colleagues investigated live specimens of two species of African spiny mouse (Acomys kempi and Acomys percivali) captured over the course of three years from rocky outcroppings in central Kenya.

Analysis of spiny mouse skin revealed it was 20 times weaker than the skin of lab mice, requiring 77 times less energy to tear. This breakaway skin likely helps spiny mice escape the clutches of predators such as snakes, owls and eagles, Seifert said.

When the researchers cut small wounds in the skin of these rodents, new layers of tissue that would later go on to become skin grew quickly over the injured areas, covering wounds 0.2 inches (4 millimeters) across after three days, compared with the five to seven days it took lab mice to do the same. Damaged ears with holes punched in them even regenerated hair follicles and cartilage without scarring.

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"The fact that these mice can regenerate such large ear holes ? 4 millimeters ? is surprising to me," Seifert said.

Healing wounds in spiny mice apparently deposit collagen fibers that form scars far more slowly and in lower abundances than in lab mice. Wounded ears also grew masses of cells similar to blastemas, transient structures used by animals such as salamander to rebuild missing tissues. "It is thought that one of the main constraints on regenerating appendages in humans ? or other mammals, for that fact ?is the failure to form a blastema," Seifert said.

These findings suggest that mammals might retain a higher capacity for regeneration than is believed. Seifert now wants to figure out what molecular mechanisms these spiny mice use to instruct blastema-like structures to form.

The scientists detail their findings in the Thursday issue of the journal Nature.

Source: http://www.msnbc.msn.com/id/49186761/ns/technology_and_science-science/

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Does Dr. Oz Vampire Hormone Advice Apply Toward Autism?

Melatonin is sometimes referred to as ?the Vampire Hormone? because it is a hormone that sleeps during the day and rises at night to provide people with a normal, restful sleep cycle. However, rather than making one feel rested and refreshed in the morning, taking an over-the-counter melatonin supplement can leave a person feeling drained in the morning as reported in an recent episode of The Dr. Oz Show. In addition, a guest expert on the show--among others--recommends against giving melatonin to children. But what about autistic children where research indicates supplemental melatonin may be the things dreams are made of for frustrated and worried parents of autistic children?

The following is a look at two views/concerns of supplemental melatonin use in both adults and autistic children.

On the Dr. Oz Show, Dr. Oz addresses the growing health problem of adults who are having difficulty sleeping may be compounding their sleep deficiency by taking melatonin supplements too often and in too high of doses that are leaving people exhausted and ill. According to special guest and sleep specialist Dr. Michael Breus Ph.D., part of the problem has to do with people believing that melatonin is a safe and natural sleeping pill or a safe and natural sleep aid as is often advertised on melatonin bottle labels.

?Here?s the problem?it?s marketed as a natural sleeping pill. It?s not a sleeping pill?it?s a sleep regulator. What melatonin does is that it kind of fakes your body out and makes you think that it?s nighttime,? says Dr. Breus. ?It regulates your sleep, it does not initiate sleep.?

Another problem, explains Dr. Breus is that people often take the wrong dose at the wrong time, which further exacerbates a person?s sleep difficulties.

?The only amount of melatonin that you would really need?if you even need it?is approximately 1 mg, because that?s how much it takes to get your plasma concentrations levels up so that it?s up in your bloodstream and having that effect of kind of tricking your brain into thinking that it?s nighttime. Anything over that is overkill?period,? says Dr. Breus. When taking melatonin, he says that it should only be taken 90 minutes before bedtime to give it time to kick in and work.

Another problem with melatonin abuse is that consumers are misled by marketing into believing that because it is natural that it is safe and can be treated like any other supplement. He points out that melatonin is not a vitamin or some supplement, but that it is a hormone and he makes the point of that hormone replacement therapy (HRT) requires a doctor?s visit and a prescription, and so should melatonin since it is a hormone.

Dr. Breus states that cases where melatonin use may be appropriate for someone includes cases such as being a shift worker who needs to regulate their sleep time or someone who suffers from jet lag. But when it comes to children, he cautions viewers that melatonin is not appropriate.

?Nothing could be worse than giving a child melatonin at this point because we don?t know what can happen?that?s my biggest fear,? says Dr. Breus. ?I?m not saying that I know definitely things are going to happen here, I?m saying that we don?t know what?s going to happen.?

But what about melatonin for autistic children who often have difficulty in going to sleep?

As it turns out Dr. Breus is not alone in believing that children should not be given melatonin. Dr. David Clark?a board-certified Chiropractic Neurologist?who has lectured on learning/behavior problems such ADHD, Autism and Dyslexia, says that giving an autistic child melatonin is ?a huge mistake.? He explains that melatonin has a type of push and pull relationship with cortisol where cortisol levels are high in the morning and low at night, whereas melatonin is low in the morning and high at night.

?Many kids have a sleep problem, but not because of a melatonin problem. The autistic child has a sleep problem due to cortisol problems?it could be a misfiring brain, it could be a gut infection, it could be food intolerance, it could be an autoimmune condition that is causing that. But giving a kid melatonin and not investigating those other factors, you are really doing your child a disservice. When you give a child melatonin?you are disturbing the normal cortisol rhythm and that can have some disastrous effects.?

Dr. Clark explains that when some parents report seeing a benefit from giving their autistic child melatonin it is because melatonin acts as an antioxidant that can calm down inflammation in the brain; however, this fails to treat the real reason why the child has an inflammation to begin with. His point being that detective work is needed to see if an autistic child is suffering from other underlying causes such as a food intolerance or an autoimmune system dysfunction before turning to melatonin as a solution.

In a recent article published in the Journal of Autism and Developmental Disorders, researchers report positive results from a 14-week study where autistic children with sleep difficulties benefited from taking varying doses of melatonin before going to bed. Their data showed that in most of the autistic children studied, dosages at 1 or 3 mg was effective within week 1 of treatment, maintained its effects over several months, was well tolerated and safe, and showed improvement in sleep and behavior.

However, the data also showed benefits in some children only after taking doses as high as 6 mg nightly, which was a major point in The Dr. Oz Show?that most adults were over-medicating themselves by taking more than the recommended I mg per day for only a few days, and that the high doses were causing health problems. The fear of treating autistic children with melatonin voiced by Dr. Clark is that the pineal gland (the body?s natural source of melatonin) will atrophy and thus lead to a lifetime dependence on taking melatonin in these children.

According to an Autism Speaks news report about the study, researchers and physicians prescribing melatonin are aware that there may be a risk with autistic children taking melatonin and that more research is needed to find out what the long-term consequence(s) if any really do exist. Furthermore, physicians for and against the use of melatonin are in accord that it should be given only under direct medical supervision and not as an OTC drug a frustrated parent may be tempted to try:

Malow (an MD and the lead author of the study) cautions that families and individuals dealing with autism-associated insomnia should consult a physician rather than try melatonin on their own. ?There are lots of causes for sleep disturbances,? she explains. ?It is vitally important to first identify and treat any underlying medical condition.? All children enrolled in the study were first evaluated by a medical specialist for potential contributory conditions such as gastrointestinal disease or sleep apnea and received treatment if needed.

Apparently what can be gleaned from the views for and against supplemental melatonin is that for now it is biologically safe and that it may prove beneficial only under specific situations and conditions and that it should not be mistaken as a type of safe and natural sleeping pill. Furthermore, experts and physicians on both sides of the fence believe that melatonin should be administered only under the supervision of a medical professional. However, it is clear that not enough is known about its long-term effects on children with autism and whether it may really lead to a lifelong dependency that should be avoided.

If supplemental melatonin eventually proves to be harmful in the long run for autistic children, it will truly have earned its name as the ?vampire hormone.? Parents with autistic children are advised to speak with their child?s physician before considering giving their child a melatonin sleep aid or other melatonin-containing product.

Image Source: Courtesy of Morgue File

References:

The Dr. Oz Show: ?Why Melatonin May be Dangerous to Your Sleep?

You Tube Video: ?Autism Mistake Melatonin?

Autism Speaks: ?More Evidence that Melatonin Eases Autism-Associated Insomnia?

?Melatonin for Sleep in Children with Autism: A Controlled Trial Examining Dose, Tolerability and Outcomes? Journal of Autism and Developmental Disorders Vol. 42, Number 8, pp. 1729-1737 (2012); Malow et al.

????????????????? "LIKE" eMaxHealth for more updates on this topic in Facebook!

Source: http://www.emaxhealth.com/8782/does-dr-oz-vampire-hormone-advice-apply-toward-autism

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Tuesday, September 25, 2012

Cop's sentencing shifts China scandal to his boss

CHENGDU, China (AP) ? China has nearly mopped up a murder scandal that has roiled the country for months, but the last step ? dealing with a fallen political star who was once among the Communist Party's most popular figures ? will be the most delicate of all.

Bo Xilai's former right-hand man and police chief, Wang Lijun, was sentenced Monday to 15 years in prison for making a thwarted defection bid, and for helping Bo's wife cover up the murder of a British businessman. Bo's wife and other figures in the scandal were sentenced previously, and Beijing is keen to settle the fate of Bo himself before a once-a-decade change in leadership expected next month.

Ever since Wang's thwarted defection bid at a U.S. consulate in February made the scandal public, the question of what to do about Bo, then a powerful party boss in Chongqing city, has bedeviled Chinese leaders. It strained relations among Communist Party power brokers just as they were cutting deals to transfer of power to younger leaders; deciding whether to prosecute him or merely purge him from the party became part of the bargaining.

Wang's trial and verdict bode ill for Bo. The official account of the trial implied that Bo ignored his wife's involvement in the murder after Wang told him about it. Though it referred to Bo by his position rather than his name, the account marked the first time in weeks of trials that Bo was mentioned in any way.

In sentencing Wang, the court emphasized his help in the murder investigation against Bo's wife, who was convicted last month, and in exposing the crimes of unspecified others.

"He apparently got credit for turning against" Bo and his wife, said Dali Yang, director of the University of Chicago Center in Beijing. "The revelation against Bo Xilai provides ground for the central leadership to dismiss Bo formally and, if they choose to do so, presumably to bring criminal charges."

Debating Bo's fate is one of the issues that has delayed announcement of a National Party Congress, a pivotal event in installing the new generation of leaders. With verdicts in for Wang and Bo's wife out of the way, leaders are next expected to announce dates for the congress and for a preparatory meeting to deal with Bo.

"The lack of a date for the congress appears to be evidence still of divisions over Bo and the final leadership lineup, as well as questions of political reform and other sensitive issues," said Jean-Pierre Cabestan, head of the department of government and international studies at Hong Kong Baptist University.

Bo's case is extremely sensitive because of his political pedigree and his popularity. The son of one of the communist state's founding fathers, Bo has deep connections across the party, government and military. He was one of 25 Politburo members and became popular nationwide through high-profile policies in Chongqing, including a crackdown on organized crime run with police chief Wang.

Bo seemed destined for the uppermost rung in the leadership before the scandal sidelined him in April. But his overt maneuvering for a top political job, the excesses of his and Wang's anti-mafia crusade and a publicity campaign to promote communist culture angered other leaders.

Given the leadership's ultimate control of the courts, the trials of Wang and Gu Kailai, Bo's wife, were likely part of pre-packaged arrangements that include a resolution of Bo's fate. Both Wang and Gu, who was given an effective life sentence, confessed to the crimes they were charged with, and both declined to appeal.

Bo was not called as a witness ? or even mentioned by name ? in the official accounts of either Gu's or Wang's trial, a sign of how the party is seeking to guide the process and minimize the impact, National University of Singapore China expert Bo Zhiyue.

"You could see this as an attempt at damage control," said Bo, who is not related to the disgraced Chinese leader.

The scandal has been the messiest, most public one Communist Party leaders have had to confront in decades, leading to Bo's removal from the leadership, his wife's confession to the murder, and sharpening divisions among the leaders.

Wang's trial and conviction mark the spectacular downfall of a publicity-grabbing police official who rose to nationwide fame by leading Chongqing's high-profile but law-bending crusade against organized crime.

According to the official account of his trial, Wang had grown close to Gu and covered up the murder of Briton Neil Heywood last November. After becoming estranged from Gu, and later Bo, Wang fled to the U.S. Consulate in Chengdu, fearing for his life.

The account said Wang secretly recorded Gu's confession to poisoning Heywood, a business associate whom she said had threatened her son's safety in a dispute over money.

The account portrays Wang as unbound by the law, ordering the surveillance of people without authorization and taking bribes from businessmen connected to Bo in exchange for releasing suspects from detention.

It said that after his falling out with Gu and Bo, Wang ordered subordinates to gather up the evidence and in February fled to the U.S. Consulate, where he sought political asylum, though he later surrendered to Chinese authorities. Gu was convicted of the murder last month and given a suspended death sentence.

___

Follow Gillian Wong on Twitter: http://twitter.com/gillianwong

Source: http://news.yahoo.com/cops-sentencing-shifts-china-scandal-boss-084450666.html

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Chronic kidney disease a warning sign independent of hypertension or diabetes

ScienceDaily (Sep. 25, 2012) ? Two new studies from the Johns Hopkins Bloomberg School of Public Health and the Chronic Kidney Disease Prognosis Consortium found that the presence of chronic kidney disease itself can be a strong indicator of the risk of death and end-stage renal disease (ESRD) even in patients without hypertension or diabetes. Both hypertension and diabetes are common conditions with chronic kidney disease with hypertension being the most prevalent.

The studies were released online in advance of publication in The Lancet.

Chronic kidney disease affects 10 to 16 percent of all adults in Asia, Europe, Australia and the United States. Kidney function is measured by estimating glomerular filtration rate and kidney damage is often quantified by measuring albumin, the major protein in the urine standardized for urine concentration.

In the hypertension meta-analysis, low kidney function and high urine protein was associated with all-cause and cardiovascular mortality and ESRD in both individuals with and without hypertension. The associations of kidney function and urine protein with mortality outcomes were stronger in individuals without hypertension than in those with hypertension, whereas the kidney function and urine protein associations with ESRD did not differ by hypertensive status.

In the diabetes analysis, individuals with diabetes had a higher risk of all-cause, cardiovascular mortality and ESRD compared to those without diabetes across the range of kidney function and urine protein. Despite their higher risks, the relative risks of these outcomes by kidney function and urine protein are much the same irrespective of the presence or absence of diabetes.

"Chronic kidney disease should be regarded as at least an equally relevant risk factor for mortality and ESRD in individuals without hypertension as it is in those with hypertension," said Bakhtawar K. Mahmoodi, MD, PhD, lead author of the hypertension analyses.

"These data provide support for clinical practice guidelines which stage chronic kidney disease based on kidney function and urine protein across all causes of kidney disease. The conclusions are strengthened by the findings of leading studies and the participation of investigators from 40, countries and a detailed analysis of over 1 million participants," said Josef Coresh, MD, PhD, MHS, the Consortium's principal investigator and professor in the Bloomberg School's Department of Epidemiology.

"Association of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis" (lead author, Bakhtawar K. Mahmoodi, MD, PhD, from the Johns Hopkins Bloomberg School of Public Health and University Medical Center Groningen, the Netherlands) and "Association of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis" (lead author Caroline Fox, MD, from the Framingham Heart Study) were written by the Chronic Kidney Disease Prognosis Consortium (CKD-PC), which includes approximately 200 collaborators and data from 40 countries.

The US National Kidney Foundation and a variety of sources such as national institutes of health and medical research councils as well as foundations and industry sponsors supporting the authors and collaborating cohorts of the CKD-PC.

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Story Source:

The above story is reprinted from materials provided by Johns Hopkins Bloomberg School of Public Health, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal References:

Bakhtawar K Mahmoodi, Kunihiro Matsushita, Mark Woodward, Peter J Blankestijn, Massimo Cirillo, Takayoshi Ohkubo, Peter Rossing, Mark J Sarnak, B?n?dicte Stengel, Kazumasa Yamagishi, Kentaro Yamashita, Luxia Zhang, Josef Coresh, Paul E de Jong, Brad C Astor. Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis. The Lancet, 2012; DOI: 10.1016/S0140-6736(12)61272-0
Caroline S Fox, Kunihiro Matsushita, Mark Woodward, Henk JG Bilo, John Chalmers, Hiddo J Lambers Heerspink, Brian J Lee, Robert M Perkins, Peter Rossing, Toshimi Sairenchi, Marcello Tonelli, Joseph A Vassalotti, Kazumasa Yamagishi, Josef Coresh, Paul E de Jong, Chi-Pang Wen, Robert G Nelson. Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. The Lancet, 2012; DOI: 10.1016/S0140-6736(12)61350-6

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/H_mKgdz8YwU/120925171224.htm

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Monday, September 24, 2012

Nine killed in Nepal avalanche

KATHMANDU (Reuters) - An avalanche swept away climbers and their camps on the world's eighth highest mountain in northwestern Nepal on Sunday, killing at least nine climbers, with another four missing, police said.

Five climbers were rescued.

Police inspector Basant Mishra said the bodies of a German climber and a Nepali guide were recovered from the snow on the 8,163-metre (26,781-foot) Mount Manaslu, about 100 km (60 miles) northwest of Kathmandu.

"Rescue pilots have spotted seven other bodies on the mountain," Mishra said. At least five injured people had been rescued by helicopters and flown to Kathmandu, he said.

The accident took place at 7,000 meters (22,950 feet), making it difficult for land rescue teams to reach.

Helicopters were dispatched to the remote area to look for those missing after the early morning accident, but cloud and fog were complicating rescue efforts, Mishra said.

Details of the avalanche and the nationality of the missing climbers were not clear.

Hundreds of foreign climbers flock every year to Himalayan peaks in Nepal, which has eight of the world's 14 highest mountains, including Mount Everest. September marks the beginning of the autumn climbing season which runs through November.

In the last major accident in the area, at least 42 people including 17 foreigners, were killed in heavy snowfall in the Mount Everest region in 1995.

(Reporting by Gopal Sharma; Editing by Ron Popeski)

Source: http://news.yahoo.com/avalanche-hits-climbers-nepal-two-dead-13-missing-100635481.html

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Storm targets "baby boomers" | Bundaberg Crime | Robberies ...

COLLAPSED financial company Storm Financial targeted "baby boomers" at retirement age and used the lending power of Australian banks "motivated by profit", a court has heard.

Lawyer Allan Myers, acting for Australian Securities and Investments Commission, told the Federal Court in Brisbane how Storm Financial deliberately targeted "ordinary people" with little experience in the stock exchange and welcomed them into the "Storm family".

He said Storm founders Emmanuel and Julie Cassimatis described these people as an "untapped and unlimited market".

They told their clients it was more financially rewarding to invest in the share market than in real estate of cash deposits, urging them to double borrow against their assets.

The Cassimatises created an aura of success through photos of with the "rich and successful" such as James Packer and Bill Clinton, which were shown in court.

In his opening address, Mr Myers said Storm, Bank of Queensland and Macquarie Bank shared responsibility in these "ordinary investors" losing billions of dollars.

He said a year before Storm collapsed, the company had more than 3000 "Stormified" clients, was managing $5 billion worth of funds and had 14 offices along Australia's east coast.

"The Storm scheme caused loss to the many participants in it," he said.

"The banks, on the other hand, made large profits."

Mr Myers said ASIC sought to prove Storm was running a managed investment scheme which should have been registered under Australia's Corporations Act.?

He said ASIC also sought to prove the banks were "knowingly concerned" with the scheme and were "motivated by profit".

"ASIC seeks declarations that Macquarie Bank and Bank of Queensland were involved in Storm's contravention of the registration position in relation to the managed investment scheme," he said.

Mr Myers said Storm's business model involved generating fees through promoting their standardised leverage investment program to the public.
He said investors would pay a "substantial upfront payment of 7% of the capital investment".

"Once you're in the Storm system, all you have to do, having ticked the boxes, is sit back and relax and wait until you got richer," he said.

"We all know what the end is, it's tears. Because having leveraged yourself, you are exposed to market volatility.

"They were back to where they started after 40 years of hard work."

Mr Myers said he aimed to prove the banks "knew what was happening" and "knew the risks" but they "were in it in order to make profits".

He said they did not have to help Storm arrange home or margin loans at reduced interest rates with higher borrowing limits.

"A person generally not experienced in financial matters but who is comfortably off, in a home not mortgaged or mortgaged to a modest extent and perhaps having other assets such as superannuation, is put into the Storm system," he said.

"The sorts of people we are talking about are generally ... persons who have retired or are reaching retirement age, they've worked and saved and they have a few assets behind them to support them in the later years of their life.

"Storm encouraged these persons to mortgage the assets they have and arranged for those borrowings.

"Then, funds having been liberated as a result of those mortgages, Storm arranges their investment in index funds promoted by Storm.

"In turn the investment in those index funds is mortgaged again by margin loans to increase the borrowings, so it's a double borrowing.

"All of this was based upon a notion those who controlled Storm had, that property was not a safe investment, was likely to decline in value and you should be in a share market."

The trial continues.

A class action involving Storm victims tied up with the Commonwealth Bank has been adjourned and will be heard separately.

Tony Morris, acting for victims, said this was the most "inexpensive and efficient way" forward so victims could properly assess a Commonwealth Bank settlement. ?

Source: http://www.news-mail.com.au/story/2012/09/24/storm-targets-baby-boomers/

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NBA 2K13 Oklahoma City Thunder vs. Miami Heat ? Full Game (Video)

NBA 2K13 Oklahoma City Thunder vs. Miami Heat View this video of the upcoming basketball game NBA 2K13, it?s a full game (4 quarters) between The Oklahoma City Thunder vs. The Miami Heat.

Incase you missed 2K?s live stream today, this is the full game. Ronnie 2K is the Thunder and Chris Manning is the Heat. They are playing on All Star difficulty. Lots of new information is shown so enjoy.

NBA 2K13 is rated E for Everyone by the ESRB and will be available on October 2, 2012 in North America and October 5, 2012 internationally for the Xbox 360, PlayStation3, PSP (PlayStation?Portable) system, Wii system and Windows PC.

The Wii U version of the title will be available during the holiday season. Fans are encouraged to pre-order now at participating retailers in order to receive the NBA All-Star content on day one at no extra cost.

Source: http://www.sohood.com/2012/09/nba-2k13-thunder-vs-heat-full-game-video/?utm_source=rss&utm_medium=rss&utm_campaign=nba-2k13-thunder-vs-heat-full-game-video

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Reds beat Dodgers 6-0, clinch NL Central

Cincinnati Reds starting pitcher Mat Latos leaves the field after the Reds defeated the Los Angeles Dodgers 6-0 to clinch the National League Central Division in a baseball game on Saturday, Sept. 22, 2012, in Cincinnati. (AP Photo/Tom Uhlman)

Cincinnati Reds' Jay Bruce (32) hugs teammate Scott Rolen after they defeated the Los Angeles Dodgers 6-0 to clinch the National League Central Division in a baseball game on Saturday, Sept. 22, 2012, in Cincinnati. (AP Photo/Al Behrman)

Cincinnati Reds starting pitcher Mat Latos (55) celebrates with teammates after they defeated the Los Angeles Dodgers 6-0 to clinch the National League Central Division in a baseball game on Saturday, Sept. 22, 2012, in Cincinnati. (AP Photo/Al Behrman)

Cincinnati Reds players mob relief pitcher Aroldis Chapman, center, after they defeated the Los Angeles Dodgers 6-0 to clinch the National League Central Division in a baseball game on Saturday, Sept. 22, 2012, in Cincinnati. (AP Photo/Al Behrman)

Cincinnati Reds right fielder Jay Bruce catches a fly ball hit by Los Angeles Dodgers' Mark Ellis in the first inning of a baseball game on Saturday, Sept. 22, 2012, in Cincinnati. (AP Photo/Al Behrman)

CINCINNATI (AP) ? General manager Walt Jocketty hit the "send" button on his cellphone right at the final out, informing his manager that the Reds' championship celebration was on.

And with a familiar swing getting them there.

Jay Bruce was Cincinnati's Mr. Clinch again, hitting the homer that started the Reds toward a 6-0 win over the Los Angeles Dodgers on Saturday that made good on their second try for the title. The only thing missing was the manager.

Dusty Baker spent another day in a Chicago hospital getting treated for an irregular heartbeat. Jocketty texted congratulations to the 63-year-old Baker on his fifth division title as a manager, including two during the last three years with Cincinnati.

"He is here everywhere," owner Bob Castellini said, standing in the middle of a soaked clubhouse that had beer and champagne dripping from the ceiling. "He is here in spirit, and everybody knows he's here. We hope to see him tomorrow."

The players toasted Baker before drenching each other.

"It's a shame he's not here," third baseman Scott Rolen said. "He digs this stuff. He's missed, there's no doubt about that."

The Reds videotaped the celebration, along with best wishes, to send to Baker. When they clinched two years ago, Baker wound up in the middle of a players' huddle, getting joyously soaked.

The 2010 party started with a dramatic Bruce homer, a first-pitch leadoff shot in the ninth against Houston's Tim Byrdak. On Saturday, he led off the fourth inning with a first-pitch homer off rookie Stephen Fife (0-2), putting Cincinnati ahead to stay with his team-leading 34th of the season.

"It's not the same as two years ago, but I'll take it," Bruce said. "We've been taking care of business for quite a while, so we knew this was coming. Today is a nutshell of what we've been doing all season."

Mat Latos (13-4) allowed six hits and didn't walk a batter in eight innings. Left-hander Aroldis Chapman made his first appearance since Sept. 10 ? a tired shoulder had sidelined him ? and finished it off by getting Hanley Ramirez to hit into a double play off a 99 mph fastball.

The celebration was on, though more subdued than two years ago.

"A couple of years ago, we were a surprise," said Joey Votto, who was the NL MVP that season. "It kind of crept up on us. We didn't expect it. This year, we felt we had something to prove."

As the Reds closed in on the final outs, second baseman Brandon Phillips pretended he was shaking a bottle of champagne and spraying it everywhere while sitting on the bench in the dugout. Phillips says the only other time he's had champagne was during the 2010 clubhouse celebration.

After the final out, players formed a huddle to the side of the mound, with pitcher Johnny Cueto spraying them with a bottle of water. An attendant rolled out a cart of gray championship shirts and hats.

Cincinnati became the first team in the majors to clinch a division title this season, leaving it with one goal left. The Reds are vying with Washington for the NL's top seed in the playoffs, both with 92 wins that lead the majors.

It's unclear when Baker will be back. The three-time manager of the year also won division titles with the Giants and Cubs. Baker reached the World Series once as a manager, losing a Game 7 against the Angels in 2002, his final season in San Francisco.

The Reds had their first opportunity to take the title on Friday night, but lost 3-1 to the Dodgers in 10 innings. Bruce had a chance to win it with another game-ending homer, but struck out leading off the ninth.

A day later, Bruce connected, Phillips added a solo homer, and rookie Todd Frazier singled home a run for more than enough. The Reds added three runs in the eighth, aided by reliever Jamey Wright's throwing error.

The Dodgers lost for the 11th time in 16 games, a swoon that has dropped them out of a wild-card spot. They trail St. Louis by three games and Milwaukee by a half-game for the final playoff berth.

Cincinnati's 92nd win is another high point under Baker, who took over in 2008 when the club was rebuilding with young stars Bruce, Votto and Cueto. The Reds improved each of the first two seasons, then became champions ahead of schedule by winning 91 games in 2010 to secure their first postseason appearance in 15 years.

Their inexperience showed in the playoffs, where the Reds got no-hit by Roy Halladay and swept by the Phillies in three games.

Things unraveled last year, when the front office decided to bring the team back virtually intact rather than upgrading its problem areas. Three of the five starting pitchers got hurt or sick during spring training, and several veterans had disappointing seasons, resulting in a third-place finish.

Cincinnati learned from its mistakes. The Reds traded two former first-round picks and starter Edinson Volquez to San Diego for Latos. Then they gave Votto an extra 10 years and $225 million on his contract.

The investments paid off in the first year.

"It's special because we've been there, we've done that," Castellini said. "We've also known how to get blown out in three (playoff) games. We don't feel we're going to let that happen again. I know we all feel that way. We're pretty confident. We'll see what happens."

Baker did some of his best managing during the season. The back end of the bullpen ? closer Ryan Madson, setup relievers Nick Masset and Bill Bray ? got wiped out by injuries during spring training. Baker eased Chapman into the unfamiliar closer's role, and he set a club record with 27 consecutive saves.

The gloomiest moment became a turning point.

Votto was the only consistent hitter going into July. He tore cartilage in his right knee and needed two operations. Baker was forced to juggle his lineup and batting order, trying to figure a way to make up for Votto's productivity and stay in the race for the next six weeks.

It worked beautifully. The Reds went 32-16 without Votto, pulling into a commanding lead in the NL Central. They were closing in on clinching the division when they went to Chicago this week, then had another setback. Baker felt bad on Wednesday and was taken to a Chicago hospital for treatment of his irregular heartbeat.

If Phillips gets his way, Baker won't miss out on the celebration entirely.

"I was looking forward to splashing some stuff in his face," Phillips said. "I saved a bottle to splash on him when he gets back."

NOTES: Los Angeles plans to start RHP Aaron Harang on short rest Sunday rather than go with LHP Clayton Kershaw, who hasn't pitched in a game since Sept. 11 because of a sore hip. He threw 20 pitches in the bullpen on Friday without problem. ... Dodgers C A.J. Ellis grounded out twice, extending his slump to 0 for 28.

___

Follow Joe Kay on Twitter: http://twitter.com/apjoekay

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-09-22-Dodgers-Reds/id-42dd9bfac78b4b56ae80bfcd1191f441

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Sunday, September 23, 2012

Obama seeks victory in Wisconsin under clouds of recall, Ryan (reuters)

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Saturday, September 22, 2012

Noonan: The Romney Campaign Needs a New CEO (WSJ)

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Friday, September 21, 2012

United tops Union, moves into 4th in East

Associated Press Sports

updated 10:31 p.m. ET Sept. 20, 2012

CHESTER, Pa. (AP) - Lionard Pajoy scored in the 67th minute to lead D.C. United to a 1-0 victory over the Philadelphia Union on Thursday night.

D.C. (14-10-5) moved into fourth place in the Eastern Conference, one point ahead of Houston and two ahead of Columbus.

Philadelphia (7-14-6) remained ninth in the East, one point behind New England. The Union's stretched their winless streak to eight matches, falling to 0-4-4 since beating the Revolution 2-1 on July 29 - and have scored just four goals in that span.

United scored after Chris Pontius approached the box and drew Union goalie Zac MacMath out of the goal. Pontius passed it to Pajoy, who stopped the ball and sent it into the wide-open net for his seventh goal of the season - and second since being traded from Philadelphia to D.C. on Aug. 16.

More news

Dempsey turns in dandy debut

PST: Winger played 76 minutes for Tottenham. He didn't score in 0-0 tie, but there was little doubt that he fit right in with very little adjustment.

Source: http://nbcsports.msnbc.com/id/49113785/ns/sports-soccer/

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Herbal Menopause Supplement Often Contains Other Species, DNA Bar Coding Reveals

Genetic analyses found herbs similar to black cohosh were being sold in commercial preparations of the popular remedy, possibly explaining mixed results and casting doubt on supplement ingredient label accuracy

By Katherine Harmon

black cohosh supplement A pure pill? Some black cohosh pills sequenced did not contain black cohosh at all, but instead different species of plant entirely. Image: iStockphoto/OlgaMiltsova

When hormone replacement therapy was found to put some menopausal women at increased risk of cancer and cardiovascular disease, many went in search of safer treatments to decrease their symptoms. In the ensuing decade black cohosh has won out as an overwhelming consumer favorite, now reaping millions of dollars in sales each year.

But controlled trials of this supplement have seen mixed results, sometimes showing it to be effective in relieving hot flashes, sleep disruptions, mood swings and other symptoms whereas other times revealing it to be ineffective. And some case reports even suggest that it can be toxic, damaging the liver.

This messy track record gave Damon Little, a bioinformaticist at The New York Botanical Garden (NYBG), and his colleagues an idea: What if patients?in these trials and out in the community?were not always taking pure, actual black cohosh (Actaea racemosa), but one or more related species? Fortunately, they had just the tool on hand to figure that out: DNA barcoding.

Using this technology, which locates and sequences specific areas of a plant's genome (specifically, two matK gene nucleotides), they were able to determine that one quarter of commercially available "black cohosh" pills were not the herb at all. Their findings were published this July in the Journal of AOAC International.

"Misidentification and adulteration in black cohosh supplements [has been] known for many years as a matter of concern," notes Rolf Teschke, an internist at the Teaching Hospital of the Johann Wolfgang Goethe University in Frankfurt and who was not involved in the new research. "The present study confirms?but extends?previous findings."

Unlike drugs, however, supplements are not required to be tested for safety or efficacy by the U.S. Food and Drug Administration before they hit the market. And testing to make sure the contents match the label are much more lax than it is for pharmaceuticals, opening the opportunity for mislabeling, whether it is accidental or intentional.

Wild roots
Black cohosh has been used traditionally by Native Americans as a natural remedy for a variety of ailments. It is often harvested in the wild, where it grows in similar environments to many of its close cousins that look very similar. And some species of Actaea are suspected to be toxic to humans. "Unless you're looking very carefully, you can't assume that any black cohoshlike thing is actually black cohosh," Little says. In eastern North America, where black cohosh grows, it is not uncommon to also find yellow cohosh (A. pachypoda and A. podocarpa) and baneberry (A. spicata and A. rubra). During harvesting, the rhizomes (buried stems) are often collected and then ground up to make the supplements, leaving telling botanical clues, such as leaf shape, forever lost.

In recent years, with the vast increase in the herb's sales, commercial growing operations have also sprung up in North America as well as Europe and Asia.

David Baker, a gynecologist at Stony Brook University Medical Center, had many patients who took black cohosh, but he was intrigued by the ambiguity of the medical literature on the supplement. So he, Little and their colleague at the NYBG, Dennis Stevenson, wanted to see if all of these pills labeled as black cohosh were, indeed the correct species.

Source: http://rss.sciam.com/click.phdo?i=13f047f19b96e1edec053cbd2da60af4

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Sony Xperia T review: a new 4.5-inch smartphone flagship that isn't quite new enough

More Info

Sony's Xperia T goes by a few names. Depending on which country you're in, you might pick it up as the Xperia GX, or possibly even the TX. The final review sample that's been passed our desk, however, is the Xperia T, the European HSPA version, headed to O2's UK stores in the coming weeks, at which point it will be free on £36 per-month contracts and likely replace the Xperia S as Sony's Android flagship. In comparison to Sony's Spring smartphone, there's a similar 720p display, now stretched out to 4.6 inches, a different 13-megapixel camera, a new 1.5GHz Snapdragon S4 processor and Android ICS -- with the promise of Jelly Bean soon after it hits store. The Xperia T also revives a familiar hardware curve and has picked up onscreen Android buttons on its design journey. Design twists and promises of the latest OS aside, has Sony finally built a top-tier phone capable of going toe-to-toe with the smartphone heavyweights? Have a look after the break.

Gallery: Sony Xperia T review

Continue reading Sony Xperia T review: a new 4.5-inch smartphone flagship that isn't quite new enough

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Absolute Rights Publishes Eightieth Edition of Popular Newsletter

The semiweekly Newsletter from Absolute Rights has been released, containing articles on pro-Muslim censorship, Afghanistan violence, and Presidential polls.

Austin, TX (PRWEB) September 20, 2012

Absolute Rights, the leading freedom protecting and civil rights informational publication, has published the eightieth edition of their semiweekly Newsletter. This milestone coincides with a current news story about the Middle Eastern violence in response to an anti-Islam movie, as well as an attack on a Coalition Forces military base in Afghanistan, and the most recent Presidential polls.

The main article was written by Tim Young, Absolute Rights? Managing Editor. Entitled ?Your First Amendment Rights Under Attack,? the Newsletter piece related the recent anti-Islam video to America?s Freedom of Speech issue. While the administration denounced the video, Young said that it may lead to further restrictions on what people can say and what they can?t.

?The problem with the limitations of free speech, and I have said this before on Absolute Rights, is that when you begin to take one piece of it away, you open yourself up to have more and more taken away until it?s practically illegal to say anything that you want to say,? Young wrote.

?Freedom of speech is why we have a lot of disgusting things in our society, but it?s also why we can stand up for ourselves and speak our minds against the government,? Young said in the article.

The Crisis Ops portion of the Newsletter covers the proper footwear to have in a survival situation. ?What you will want is a good pair of boots,? the article said. ?Something light weight and has a good all-terrain coating to them. You?ll want something that has a tough exterior and can keep you warm. You?ll also want something that has a tough exterior and can handle taking a few hits.?

Global Watch, the international affairs section, highlighted the recent attacks on an Afghanistan military base by Afghani insurgents dressed in American uniforms. ?The strategy of wearing US military uniforms is not unique to this attack,? said the article. ?Afghan insurgents had worn them before to attack coalition troops in May of 2010. This strategy was also used in Iraq in 2007.?

The final part of the Newsletter is the Contender?s Corner, where Young analyzes the latest polls on the Presidential race.

?If you?re like me,? said Young, ?you?ve probably been a little bit more than shocked that Mitt Romney has been making as many slip-ups as he has in the media spotlight. Not only am I shocked at that, but also his inability to fight back against the media when they jump down his throat [for] misspeaking or saying something inappropriate.?

The Absolute Rights Newsletter is sent to thousands of Absolute Rights email subscribers as part of the never-ending effort to bring relevant and captivating content directly to readers. Newsletters are distributed via email and the articles then appear online at AbsoluteRights.com.

Tim Young, a native of Baltimore, Maryland, joined Absolute Rights in the spring of 2012 and brought his brutally honest opinions with him. He has been consulted as an expert on campaign, social security, health care and labor policies. A professional stand-up comic, Young combines his political and comedic background to add a captivating voice to Absolute Rights? mission of rights protection.

Absolute Rights informs patriotic Americans on their given rights, plus helps protect those rights from government or disaster intrusion. Most importantly, it prides itself on alerting people when their rights are being threatened, creating an active and informed community. For more information, be sure to visit AbsoluteRights.com.

Paul Norwine
Absolute Rights, LLC
512-892-3022
Email Information

Source: http://news.yahoo.com/absolute-rights-publishes-eightieth-edition-popular-newsletter-080447629.html

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Thursday, September 20, 2012

Obama Meets With Aung San Suu Kyi (Voice Of America)

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China to protesters: 'Please express your patriotism in a rational and orderly fashion'

Chinese protesters followed the rules on Tuesday, obediently forming small groups and awaiting their turn to march past the Japanese embassy to express anger over disputed islands.

By Peter Ford,?Staff writer / September 18, 2012

A demonstrator shouts slogans during a protest in front of a Chinese national flag on the 81st anniversary of Japan's invasion of China, in Shanghai, Sept. 18. Anti-Japan protests reignited across China on Tuesday, the emotional anniversary marking Tokyo's occupation of its giant neighbor, escalating a maritime dispute which has forced major Japanese brandname firms to suspend business there.

Carlos Barria/Reuters

Enlarge

The first sign of just how closely the Chinese authorities were monitoring and controlling today?s anti-Japanese demonstrations here came on my cellphone.

Skip to next paragraph Peter Ford

Beijing Bureau Chief

Peter Ford is The Christian Science Monitor?s Beijing Bureau Chief. He covers news and features throughout China and also makes reporting trips to Japan and the Korean peninsula.

Single-atom writer a landmark for quantum computing

ScienceDaily (Sep. 19, 2012) ? A research team led by Australian engineers has created the first working quantum bit based on a single atom in silicon, opening the way to ultra-powerful quantum computers of the future.

In a landmark paper published September 19 in the journal Nature, the team describes how it was able to both read and write information using the spin, or magnetic orientation, of an electron bound to a single phosphorus atom embedded in a silicon chip.

"For the first time, we have demonstrated the ability to represent and manipulate data on the spin to form a quantum bit, or 'qubit', the basic unit of data for a quantum computer," says Scientia Professor Andrew Dzurak. "This really is the key advance towards realising a silicon quantum computer based on single atoms."

Dr Andrea Morello and Professor Dzurak from the UNSW School of Electrical Engineering and Telecommunications lead the team. It includes researchers from the University of Melbourne and University College, London.

"This is a remarkable scientific achievement -- governing nature at its most fundamental level -- and has profound implications for quantum computing," says Dzurak.

Dr Morello says that quantum computers promise to solve complex problems that are currently impossible on even the world's largest supercomputers: "These include data-intensive problems, such as cracking modern encryption codes, searching databases, and modelling biological molecules and drugs."

The new finding follows on from a 2010 study also published in Nature, in which the same UNSW group demonstrated the ability to read the state of an electron's spin. Discovering how to write the spin state now completes the two-stage process required to operate a quantum bit.

The new result was achieved by using a microwave field to gain unprecedented control over an electron bound to a single phosphorus atom, which was implanted next to a specially-designed silicon transistor. Professor David Jamieson, of the University of Melbourne's School of Physics, led the team that precisely implanted the phosphorus atom into the silicon device.

UNSW PhD student Jarryd Pla, the lead author on the paper, says: "We have been able to isolate, measure and control an electron belonging to a single atom, all using a device that was made in a very similar way to everyday silicon computer chips."

As Dr Morello notes: "This is the quantum equivalent of typing a number on your keyboard. This has never been done before in silicon, a material that offers the advantage of being well understood scientifically and more easily adopted by industry. Our technology is fundamentally the same as is already being used in countless everyday electronic devices, and that's a trillion-dollar industry."

The team's next goal is to combine pairs of quantum bits to create a two-qubit logic gate -- the basic processing unit of a quantum computer.

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Story Source:

The above story is reprinted from materials provided by University of New South Wales, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Jarryd J. Pla, Kuan Y. Tan, Juan P. Dehollain, Wee H. Lim, John J. L. Morton, David N. Jamieson, Andrew S. Dzurak, Andrea Morello. A single-atom electron spin qubit in silicon. Nature, 2012; DOI: 10.1038/nature11449

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_technology/~3/2-HJNcrcjAk/120919135305.htm

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Video: Matthews: Romney said exactly what he thinks

Pettitte returns, helps Yankees top Jays

NEW YORK (AP) - Andy Pettitte pitched five sparkling innings in his return from a broken leg and his bullpen barely held on, keeping the New York Yankees atop the AL East with a 4-2 victory over the Toronto Blue Jays in the opener of Wednesday's day-night doubleheader.

Source: http://www.msnbc.msn.com/id/3036697/vp/49079163#49079163

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Wednesday, September 19, 2012

Heather Morris Bikini Photos: THG Hot Bodies Countdown #82!

THG is counting down the 100 Hottest Bikini Bodies of 2012!

From now until the end of the year, we'll be paying tribute to the hottest of the hot with bikini photos galore. The competition is guaranteed to be sweltering.

LeAnn Rimes bikini pictures were honored yesterday as this very smoldering countdown continued. Keeping the hotness rolling today at #82: Heather Morris!

Heather Morris is definitely one reason to remain Glee-ful.

While the Fox hit isn't what it once was, our beloved Brittany will be covering Britney once again Thursday on the second episode of Glee Season 4. Holla!

We won't hold it against Heather for channeling Spears a second time. In fact, we wouldn't mind holding her body against us. She's in tremendous shape.

Not convinced? Then go examine more bikini evidence below. Click to enlarge the Heather Morris photos here, and check back for THG's bikini babe #81 ...